Optimide Ophthalmic Solution

Sulfacetamide Sodium 10% Eye prep
20%
Jayson Pharmaceuticals Ltd.
Pack size10 ml
Retail Price22.40

Indications

Conjunctivitis, Blepharitis, Ocular infections

Adult Dose

Ophthalmic Ocular infections Adult: Apply eye drops into the affected eye/s. May be used up to tid.

Contra Indications

Hypersensitivity; infants <2 mth.

Precautions

Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation.

Pregnancy-Lactation

C Pregnancy Category: C Lactation: Safety in nursing infants unknown; not recommended

Interactions

Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.

Adverse Effects

Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva. Potentially Fatal: Stevens-Johnson syndrome.

Mechanism of Action

Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid.

Note

Optimide 20% Ophthalmic Solution manufactured by Jayson Pharmaceuticals Ltd.. Its generic name is Sulfacetamide Sodium 10% Eye prep.